2024
Mar Aníbal-Martínez, Lorenzo Puche-Aroca, Gabriele Pumo, M. Pilar Madrigal, Luis M. Rodríguez-Malmierca, Francisco J. Martini, Filippo M. Rijli, Guillermina López-Bendito. A prenatal window for enhancing spatial resolution of cortical barrel maps. bioRxiv 2024.03.15.585193; doi: https://doi.org/10.1101/2024.03.15.585193
Leyva-Díaz, E., Wilson, E. S., & López-Bendito, G. Development has the answer: Unraveling psychiatric disorders via thalamocortical organoids. Cell stem cell, 31(3), 283–284. 2024. https://doi.org/10.1016/j.stem.2024.02.008
2023
Huerga-Gómez I, Martini FJ, López-Bendito G. Building thalamic neuronal networks during mouse development. Front Neural Circuits. 2023 Feb 3;17:1098913. doi: 10.3389/fncir.2023.1098913. PMID: 36817644; PMCID: PMC9936079.
2022
2021
Martini FJ, Guillamón-Vivancos T, Moreno-Juan V, Valdeolmillos M, López-Bendito G. Spontaneous activity in developing thalamic and cortical sensory networks. Neuron. 2021 Aug 18;109(16):2519-2534. doi: 10.1016/j.neuron.2021.06.026. Epub 2021 Jul 21. PMID: 34293296.
Alçada-Morais S, Gonçalves N, Moreno-Juan V, Andres B, Ferreira S, Marques JM, Magalhães J, Rocha JMM, Xu X, Partidário M, Cunha RA, López-Bendito G, Rodrigues RJ. Adenosine A2A Receptors Contribute to the Radial Migration of Cortical Projection Neurons through the Regulation of Neuronal Polarization and Axon Formation. Cereb Cortex. 2021 Jun 28:bhab188. doi: 10.1093/cercor/bhab188. Epub ahead of print. PMID: 34184030.
Company V, Andreu-Cervera A, Madrigal MP, Andrés B, Almagro-García F, Chédotal A, López-Bendito G, Martinez S, Echevarría D, Moreno-Bravo JA, Puelles E. Netrin 1-Mediated Role of the Substantia Nigra Pars Compacta and Ventral Tegmental Area in the Guidance of the Medial Habenular Axons. Front Cell Dev Biol. 2021 Jun 8;9:682067. doi: 10.3389/fcell.2021.682067. PMID: 34169076; PMCID: PMC8217627.
Herrero-Navarro Á, Puche-Aroca L, Moreno-Juan V, Sempere-Ferràndez A, Espinosa A, Susín R, Torres-Masjoan L, Leyva-Díaz E, Karow M, Figueres-Oñate M, López-Mascaraque L, López-Atalaya JP, Berninger B, López-Bendito G. Astrocytes and neurons share region-specific transcriptional signatures that confer regional identity to neuronal reprogramming. Sci Adv. 2021 Apr 7;7(15):eabe8978. doi: 10.1126/sciadv.abe8978. PMID: 33827819; PMCID: PMC8026135.
Kitazawa T, Machlab D, Joshi O, Maiorano N, Kohler H, Ducret S, Kessler S, Gezelius H, Soneson C, Papasaikas P, López-Bendito G, Stadler MB, Rijli FM. A unique bipartite Polycomb signature regulates stimulus-response transcription during development. Nat Genet. 2021 Mar;53(3):379-391. doi: 10.1038/s41588-021-00789-z. Epub 2021 Feb 18. PMID: 33603234; PMCID: PMC7610396.
2020
García-Guillén IM, Alonso A, Morales-Delgado N, Andrés B, Puelles L, López-Bendito G, Marín F, Aroca P. Netrin-1/DCC Signaling Differentially Regulates the Migration of Pax7, Nkx6.1, Irx2, Otp, and Otx2 Cell Populations in the Developing Interpeduncular Nucleus. Front Cell Dev Biol. 2020 Oct 20;8:588851. doi: 10.3389/fcell.2020.588851. PMID: 33195252; PMCID: PMC7606981.
2019
Riva M, Genescu I, Habermacher C, Orduz D, Ledonne F, Rijli FM, López-Bendito G, Coppola E, Garel S, Angulo MC, Pierani A. Activity-dependent death of transient Cajal-Retzius neurons is required for functional cortical wiring. Elife. 2019 Dec 31;8:e50503. doi: 10.7554/eLife.50503. PMID: 31891351; PMCID: PMC6938399.
Antón-Bolaños N, Sempere-Ferràndez A, Guillamón-Vivancos T, Martini FJ, Pérez-Saiz L, Gezelius H, Filipchuk A, Valdeolmillos M, López-Bendito G. Prenatal activity from thalamic neurons governs the emergence of functional cortical maps in mice. Science. 2019 Jun 7;364(6444):987-990. doi: 10.1126/science.aav7617. Epub 2019 May 2. PMID: 31048552.
2018
Kolodkin AL, López-Bendito G. Editorial Overview: Developmental neuroscience. Curr Opin Neurobiol. 2018 Dec;53:iii-vi. doi: 10.1016/j.conb.2018.10.010. PMID: 30449415.
Antón-Bolaños N, Espinosa A, López-Bendito G. Developmental interactions between thalamus and cortex: a true love reciprocal story. Curr Opin Neurobiol. 2018 Oct;52:33-41. doi: 10.1016/j.conb.2018.04.018. Epub 2018 Apr 25. PMID: 29704748.
López-Bendito G. Development of the Thalamocortical Interactions: Past, Present and Future. Neuroscience. 2018 Aug 10;385:67-74. doi: 10.1016/j.neuroscience.2018.06.020. Epub 2018 Jun 20. PMID: 29932982.
Martini FJ, Moreno-Juan V, Filipchuk A, Valdeolmillos M, López-Bendito G. Impact of thalamocortical input on barrel cortex development. Neuroscience. 2018 Jan 1;368:246-255. doi: 10.1016/j.neuroscience.2017.04.005. Epub 2017 Apr 13. PMID: 28412498.
2017
Gezelius H, Moreno-Juan V, Mezzera C, Thakurela S, Rodríguez-Malmierca LM, Pistolic J, Benes V, Tiwari VK, López-Bendito G. Genetic Labeling of Nuclei-Specific Thalamocortical Neurons Reveals Putative Sensory-Modality Specific Genes. Cereb Cortex. 2017 Nov 1;27(11):5054-5069. doi: 10.1093/cercor/bhw290. PMID: 27655933.
Gezelius H, López-Bendito G. Thalamic neuronal specification and early circuit formation. Dev Neurobiol. 2017 Jul;77(7):830-843. doi: 10.1002/dneu.22460. Epub 2016 Nov 4. PMID: 27739248.
Moreno-Juan V, Filipchuk A, Antón-Bolaños N, Mezzera C, Gezelius H, Andrés B, Rodríguez-Malmierca L, Susín R, Schaad O, Iwasato T, Schüle R, Rutlin M, Nelson S, Ducret S, Valdeolmillos M, Rijli FM, López-Bendito G. Prenatal thalamic waves regulate cortical area size prior to sensory processing. Nat Commun. 2017 Feb 3;8:14172. doi: 10.1038/ncomms14172. PMID: 28155854; PMCID: PMC5296753.
2016
Mezzera C, López-Bendito G. Cross-modal plasticity in sensory deprived animal models: From the thalamocortical development point of view. J Chem Neuroanat. 2016 Sep;75(Pt A):32-40. doi: 10.1016/j.jchemneu.2015.09.005. Epub 2015 Oct 13. PMID: 26459021.
Grubb MS, Hoogenraad CC, Schwabe L, López-Bendito G. Moving on: mobility for early-career neuroscientists. Eur J Neurosci.2016 Sep;44(6):2285-90. doi: 10.1111/ejn.13339. Epub 2016 Aug 2. PMID: 27421696.
Poirazi P, Belin D, Gräff J, Hanganu-Opatz IL, López-Bendito G. Balancing family with a successful career in neuroscience. Eur J Neurosci. 2016 Jul;44(2):1797-803. doi: 10.1111/ejn.13280. Epub 2016 Jun 13. PMID: 27206994.
Schwabe L, López-Bendito G, Ribeiro C. Getting published: how to write a successful neuroscience paper. Eur J Neurosci. 2016 Apr;43(8):992-6. doi: 10.1111/ejn.13215. Epub 2016 Mar 17. PMID: 26913687.
2015
Morello F, Prasad AA, Rehberg K, Vieira de Sá R, Antón-Bolaños N, Leyva-Diaz E, Adolfs Y, Tissir F, López-Bendito G, Pasterkamp RJ. Frizzled3 Controls Axonal Polarity and Intermediate Target Entry during Striatal Pathway Development. J Neurosci. 2015 Oct 21;35(42):14205-19. doi: 10.1523/JNEUROSCI.1840-15.2015. PMID: 26490861; PMCID: PMC6605421.
Barão S, Gärtner A, Leyva-Díaz E, Demyanenko G, Munck S, Vanhoutvin T, Zhou L, Schachner M, López-Bendito G, Maness PF, De Strooper B. Antagonistic Effects of BACE1 and APH1B-γ-Secretase Control Axonal Guidance by Regulating Growth Cone Collapse. Cell Rep. 2015 Sep 1;12(9):1367-76. doi: 10.1016/j.celrep.2015.07.059. Epub 2015 Aug 20. PMID: 26299962; PMCID: PMC4820248.
Castillo-Paterna M, Moreno-Juan V, Filipchuk A, Rodríguez-Malmierca L, Susín R, López-Bendito G. DCC functions as an accelerator of thalamocortical axonal growth downstream of spontaneous thalamic activity. EMBO Rep. 2015 Jul;16(7):851-62. doi: 10.15252/embr.201439882. Epub 2015 May 6. PMID: 25947198; PMCID: PMC4515124.
2014
Moreno-Bravo JA, Martinez-Lopez JE, Madrigal MP, Kim M, Mastick GS, Lopez-Bendito G, Martinez S, Puelles E. Developmental guidance of the retroflex tract at its bending point involves Robo1-Slit2-mediated floor plate repulsion. Brain Struct Funct. 2016 Jan;221(1):665-78. doi: 10.1007/s00429-014-0932-4. Epub 2014 Nov 4. PMID: 25366972; PMCID: PMC4485949.
Garel S, López-Bendito G. Inputs from the thalamocortical system on axon pathfinding mechanisms. Curr Opin Neurobiol. 2014 Aug;27:143-50. doi: 10.1016/j.conb.2014.03.013. Epub 2014 Apr 17. PMID: 24742382.
Leyva-Díaz E, del Toro D, Menal MJ, Cambray S, Susín R, Tessier-Lavigne M, Klein R, Egea J, López-Bendito G. FLRT3 is a Robo1-interacting protein that determines Netrin-1 attraction in developing axons. Curr Biol. 2014 Mar 3;24(5):494-508. doi: 10.1016/j.cub.2014.01.042. Epub 2014 Feb 20. PMID: 24560577.
2013
Benjumeda I, Escalante A, Law C, Morales D, Chauvin G, Muça G, Coca Y, Márquez J, López-Bendito G, Kania A, Martínez L, Herrera E. Uncoupling of EphA/ephrinA signaling and spontaneous activity in neural circuit wiring. J Neurosci. 2013 Nov 13;33(46):18208-18. doi: 10.1523/JNEUROSCI.1931-13.2013. PMID: 24227729; PMCID: PMC3831575.
Leyva-Díaz E, López-Bendito G. In and out from the cortex: development of major forebrain connections. Neuroscience. 2013 Dec 19;254:26-44. doi: 10.1016/j.neuroscience.2013.08.070. Epub 2013 Sep 13. PMID: 24042037.
2012
Mire E, Mezzera C, Leyva-Díaz E, Paternain AV, Squarzoni P, Bluy L, Castillo-Paterna M, López MJ, Peregrín S, Tessier-Lavigne M, Garel S, Galcerán J, Lerma J, López-Bendito G. Spontaneous activity regulates Robo1 transcription to mediate a switch in thalamocortical axon growth. Nat Neurosci. 2012 Jul 8;15(8):1134-43. doi: 10.1038/nn.3160. PMID: 22772332.
Yamamoto N, López-Bendito G. Shaping brain connections through spontaneous neural activity. Eur J Neurosci. 2012 May;35(10):1595-604. doi: 10.1111/j.1460-9568.2012.08101.x. PMID: 22607005.
Molnár Z, Garel S, López-Bendito G, Maness P, Price DJ. Mechanisms controlling the guidance of thalamocortical axons through the embryonic forebrain. Eur J Neurosci. 2012 May;35(10):1573-85. doi: 10.1111/j.1460-9568.2012.08119.x. PMID: 22607003; PMCID: PMC4370206.
Jabaudon D, López Bendito G. Development and plasticity of thalamocortical systems. Eur J Neurosci. 2012 May;35(10):1522-3. doi: 10.1111/j.1460-9568.2012.08117.x. PMID: 22606997.
Marcos-Mondéjar P, Peregrín S, Li JY, Carlsson L, Tole S, López-Bendito G. The lhx2 transcription factor controls thalamocortical axonal guidance by specific regulation of robo1 and robo2 receptors. J Neurosci. 2012 Mar 28;32(13):4372-85. doi: 10.1523/JNEUROSCI.5851-11.2012. PMID: 22457488; PMCID: PMC6622047.
López-Bendito G, Arlotta P. Cell replacement therapies for nervous system regeneration. Dev Neurobiol. 2012 Feb;72(2):145-52. doi: 10.1002/dneu.20897. PMID: 21557508; PMCID: PMC4226408.
2011
Bielle F*, Marcos-Mondéjar P*, Leyva-Díaz E*, Lokmane L*, Mire E, Mailhes C, Keita M, García N, Tessier-Lavigne M, Garel S†, López-Bendito G† (2011) Emergent growth cone responses to combinations of Slit1 and Netrin 1 in thalamocortical axon topography. Current Biology 21:1748-55. *Equal contribution. †Corresponding authors.
Bielle F, Marcos-Mondejar P, Keita M, Mailhes C, Verney C, Nguyen Ba-Charvet K, Tessier-Lavigne M, López-Bendito G, Garel S (2011) Slit2 activity on the migration of guidepost neurons shapes thalamic projections during development and evolution. Neuron 69:1085-1098.
Moldrich RX, Mezzera C, Holmes WM, Goda S, Brookfield SJ, Rankin AJ, Barr E, Kurniawan N, D, Richards LJ, López-Bendito G, Iwata T (2011) Fgfr3 regulates development of the caudal telencephalon. Developmental Dynamics 240:1586-1599.
Sánchez-Alcañiz JA, Haege S, Mueller W, Pla R, Mackay F, Schulz S, López-Bendito G, Stumm R, Marín O (2011) Cxcr7 controls neuronal migration by regulating chemokine responsivenes. Neuron 69:77-90.
2009
Little GE*, López-Bendito G*,†, Rünker AE, García N, Piñon MC, Chédotal A, Molnár Z†, Mitchell KJ† (2009) Specificity and plasticity of thalamocortical connections in Sema6A mutant mice. PLoS Biology 28:e98. *Equal contribution. †Corresponding authors.
Martini FJ*, Valiente M*, López Bendito G, Szabó G, Moya F, Valdeolmillos M, Marín O (2009) Biased selection of leading process branches mediates chemotaxis during tangential neuronal migration. Development 136:41-50. *Equal contribution
2008
López-Bendito G*, Sánchez-Alcañiz JA*, Pla R*, Borrell V, Picó E, Valdeolmillos M, Marín O (2008) Chemokine signaling controls intracortical migration and final distribution of GABAergic interneurons. Journal of Neuroscience 28:1613-1624. *Equal contribution
2007
Carney RS, Bystron I, López-Bendito G, Molnár Z (2007) Comparative analysis of extra ventricular mitosis at early stages of cortical development in rat and human. Brain Struct Funct. 212: 37–54
López-Bendito G, Flames N, Ma L, Fouquet C, Di Meglio T, Chedotal A, Tessier-Lavigne M, Marín O (2007) Robo1 and Robo2 cooperate to control the guidance of major axonal tracts in the mammalian forebrain. Journal of Neuroscience 27:3395-407.
2006
López-Bendito G*, Cautinat A*, Sanchez JA, Bielle F, Flames N, Garrat AN, Tagmale D, Role LW, Charnay P, Marin O, Garel S (2006) Tangential Neuronal Migration Controls Axon Guidance: A Role for Neuregulin-1 in Thalamocortical Axon Navigation. Cell 125:127-142. *Equal contribution
Marín O and López-Bendito G (2006) Neuronal Migration. Evolution of Nervous Systems (Striedter, G.F., and Rubenstein, J.L.R., eds) Elsevier. History of Ideas, Basic Concepts and Developmental Mechanisms
Molnár Z, López-Bendito G, Blakey D, Thompson A, Higashi S (2006) The earliest thalamocortical interactions. Development and Plasticity in Sensory Thalamus and Cortex. Springer, NY
2005
Luján R, Shigemoto R, López-Bendito G (2005) Glutamate and GABA receptor signalling in the developing brain. Neuroscience 130: 567-580
2004
López-Bendito G, Shigemoto R, Kulik A, Fairén A, Luján R (2004) Distribution of metabotropic GABA receptor Subunits GABA(B1a/b) and GABA(B2) in the rat hippocampus during prenatal and postnatal development. Hippocampus 14: 836-848
Panzanelli P, López-Bendito G, Luján R, Sassoé-Pognetto M (2004) Localization and developmental expression of GABAB receptors in the rat olfactory bulb. Journal of Neurocitology 33: 87-99
López-Bendito G, Sturgess K, Erdélyi F, Szabó G, Molnár Z, Paulsen O (2004) Preferential origin and layer destination of GAD65-GFP cortical interneurons. Cerebral Cortex 14:1122-33.
2003
López-Bendito G, Luján R, Shigemoto R, Ganter P, Paulsen O, Molnár Z (2003) Blockade of GABAB receptors alters the migration of tangentially neurons. Cerebral Cortex 13: 932-942
Kulik A, Vida I, Luján R, Haas CA, López-Bendito G, Shigemoto R, Frotscher M (2003) Subcellular localization of metabotropic GABA(B) receptor subunits GABA(B1a/b) and GABA(B2) in the rat hippocampus. Journal of Neuroscience 23: 11026-11035
Molnár Z, Higashi S, López-Bendito G (2003) Choreography of early thalamocortical development. Cerebral Cortex 13: 661-669
López-Bendito G and Molnár Z (2003) Thalamocortical Development! How are we going to get there? Nature Reviews Neuroscience 4: 276-289
2002
López-Bendito G, Chan CH, Mallamaci A, Parnavelas J, Molnár Z (2002) The role of Emx2 in the development of the reciprocal connectivity between cortex and thalamus. Journal of Comparative Neurology 451-153
Molnár Z*, López-Bendito G*, Small J, Partridge LD, Blakemore C, Wilson MC (2002) Normal development of thalamocortical projections in the SNAP-25 deficient mouse. Journal of Neuroscience 22: 10313-10323. *Equal contribution
Jones L*, López-Bendito G*, Grüss P, Stoykova A, Molnár Z (2002) Pax6 is required for the normal development of the cerebral cortex and its connections. Development 129: 5041-5052. *Equal contribution
Washbourne P, Thompson PM, Carta M, Costa ET, Mathews JR, López-Bendito G, Molnar Z, Becher MW, Valenzuela CF, Partridge LD, Wilson MC (2002) Genetic ablation of the t-SNARE SNAP-25 distinguishes mechanisms of neuroexocytosis. Nature Neuroscience 5: 19-26
López-Bendito G, Shigemoto R, Fairén A, Luján, R (2002) Differential distribution of group I metabotropic glutamate receptors during rat cortical development. Cerebral Cortex 12: 625-638
López-Bendito G, Shigemoto R, Kulik A, Paulsen O, Fairén A, Luján, R (2002) Expression and distribution of metabotropic GABA receptor subtypes GABABR1 and GABABR2 during rat cortical development. European Journal of Neuroscience 15:1766-1778
2001
López-Bendito G, Shigemoto R, Luján R, Juiz JM (2001) Developmental changes in the localization of the mGluR1α subtype of metabotropic glutamate receptors in Purkinje cells. Neuroscience 105: 413-429
Martínez-Galán JR, López-Bendito G, Luján, R., Shigemoto R, Fairén A, Valdeolmillos M (2001) Cajal-Retzius cells in early postnatal mouse cortex selectively express functional metabotropic glutamate receptors. European Journal of Neuroscience 13: 1147-1154