Guillermina López-Bendito
Guillermina López-BenditoPrincipal Investigator
Investigador Cientifico CSIC, 2014; Cientifico Titular CSIC, 2007-2014
Ph.D. in Biology, CSIC-Universidad Miguel Hernández, 2000
Email: g.lbendito@umh.es

Our research team runs several related projects studying the cellular and molecular mechanisms involved in the development of axonal connections in the brain. In particular, our aim is to uncover the principles underlying thalamocortical axonal wiring, maintenance and ultimately the rewiring of connections, through an integrated experimental programme.

Miguel Valdeolmillos
Miguel ValdeolmillosSenior Researcher
Professor of Physiology. UMH, 2000
Ph.D. in Medicine, Universidad de Valladolid 1982
Email: miguel.valdeolmillos@umh.es

I have a lasting interest in intracellular signaling in the context of cell communication. Since I joined the lab in 2013, I have been collaborating in the study of thalamic network´s development under normal conditions as well as using experimental paradigms that trigger thalamic plasticity.

Francisco J Martini
Francisco J MartiniSenior Researcher
Assistant Professor of Physiology. UMH, 2015
Postdoctoral Fellow at Biozentrum, Basel (2013-2015)
Postdoctoral Fellow at IN, Alicante (2010-2012)
Ph.D. in Neuroscience, CSIC-Universidad Miguel Hernández, 2010
Email: fmartini@umh.es

I joined López-Bendito lab in June 2015. Combining electrophysiology and calcium imaging in vivo, I study the role of spontaneous and sensory-driven activity in thalamocortical development and cortical function. 

Ana Espinosa
Ana EspinosaPostdoctoral Researcher

Postdoctoral Fellow at The Scripps Research Institute, San Diego (2010-2015)
PhD in Neuroscience, CSIC-Universidad Miguel Hernández, 2009
Email: abespinosa@umh.es

I joined the lab in October 2015. I am interested in understanding the mechanisms that specify thalamocortical neurons, and promote neuroplasticity in the brain. My research aims to restore thalamocortical circuits in sensory-deprived animals in vivo by reprogramming thalamocortical postmitotic neurons with the help of lentiviral vectors.

Anton Filipchuk
Anton FilipchukPostdoctoral Researcher
Postdoctoral Fellow at INMED, Marseille, France (2012-2013)
Ph.D. in Neuroscience CNRS-Aix-Marseille University, France, 2011
Email: afilipchuk@umh.es

Since I joined the lab in 2013, I am studying the role of spontaneous activity in thalamocortical networks in wild type and sensory-deprived animals. I am interested in the temporal correlation and spatial organisation of these networks as well as in the role of spontaneous activity in cross-modal plasticity.

Alejandro Sempere Ferrández
Alejandro Sempere FerrándezPostdoctoral Researcher
Ph.D. in Neuroscience, Instituto de Neurociencias, Alicante, 2016
Email: a.sempere@umh.es

I am specially interested in the electrophysiological properties of neural circuits during development and in the adult. Since I joined the lab in 2017, I have been investigating the activity of thalamic and cortical neurons by using whole-cell patch-clamp recordings in acute slices and in vivo.

Veronica Moreno-Juan
Veronica Moreno-JuanGraduate Student
Biology degree, University of Alicante, 2012
Email: v.moreno@umh.es

Since I joined the laboratory in 2012, I have been interested in the mechanisms by which thalamic axons influence and specify the identity of different sensory areas of the neocortex. I am currently working on the role of thalamic neurons in the processes of neuroplasticity upon sensory deprivation.

Noelia Antón-Bolaños
Noelia Antón-BolañosGraduate Student
Biology degree, University of Alicante, 2011
Email: n.anton@umh.es

Since I joined the lab in 2012, I have been working on a research project aimed to understand the capacity of thalamocortical axons to rewire and restore cortical function when an insult has occurred using functional analysis of genetic mouse models.

Álvaro Herrero Navarro
Álvaro Herrero NavarroGraduate Student
Biotechnology degree, University of Miguel Hernández, 2014
Email: a.herrero@umh.es

Since I joined the lab in 2014, I have been working on a research project aimed at testing the efficinece of reprogramming of endogenous brain cells into specific neurons using techniques of cellular characterization and retrovirus design.

Mar Anibal Martínez
Mar Anibal MartínezGraduate Student
Biology degree, University of Alicante, 2014

Email: manibal@umh.es

Since I joined the lab in 2016, I have been interested in understanding the role of high order thalamic nuclei in sensory processing and neuroplasticity upon sensory deprivation.

Irene Huerga Gómez
Irene Huerga GómezGraduate Student
Biochemistry degree, Universidad Autónoma de Madrid, 2014

Email: ihuerga@umh.es

Since I joined the lab in 2016, I am working on thalamic interneurons using molecular and cellular tools combined with specific transgenic mice.

Leticia Perez Saiz
Leticia Perez SaizGraduate Student
Biochemistry and Biomedical Sciences degree, University of Valencia, 2014

Email: leticia.perezs@umh.es

Since I joined the lab, in October 2015, I am specially interested in understanding the electrophysiological properties of thalamic nuclei and cortex in vivo.

Luis Rodríguez
Luis RodríguezLaboratory Technician
Email: luis.rodriguezm@umh.es

From 2012, I have been in charge of the maintenance of the laboratory stocks, cell cultures media, organotypic cultures, in situ hybridization and perfusion. I am also specialized in the electron microscopy technique. At present, I am doing electron microscopy in the prenatal and postnatal thalamus.

Rafael Susin
Rafael SusinLaboratory Technician
Email: rsusin@umh.es

Since I joined the laboratory in April 2012, I am in charge of the molecular biology experiments in the laboratory, such as western-blot or qPCR, as well as performing subcloning of distinct DNA constructs.

Belén Andrés Bayón
Belén Andrés BayónLaboratory Technician
Email: andres@umh.es

Since I joined the laboratory in November 2014, I am in charge of the management of the transgenic mouse lines colonies of the laboratory. I am also specialized in the in utero electroporation technique of DNA constructs in thalamus and cortex.

Helena Campos
Helena CamposAdministrative Assistant
Email: hcampos@umh.es

Since I joined the laboratory in 2010, I have been in charge of the administrative management and financial aspects of the scientific projects of the lab.

Former Laboratory Members

Henrik Gezelius. Postdoctoral Fellow from 2010-2015

Eduardo Leyva-Díaz. Ph.D. Student from 2008-2014

Current position: Postdoctoral Fellow in the laboratory of Oliver Hobert, Columbia University, New York (US)

Mar Castillo-Paterna. Postdoctoral Fellow from 2010-2014

Cecilia Mezzera. Ph.D. Student from 2008-2013

Current position: Postdoctoral Fellow in the laboratory of Maria Luisa Vasconcelos, Champalimaud, Lisbon (Portugal)

Graciela Navarro. Postdoctoral Fellow from 2010-2012

Current position: Postdoctoral Fellow in the laboratory of Luis Martinez at IN, Alicante (Spain)

Paula Marcos-Mondejar. Ph.D. Student from 2007-2012

Current position: Postdoctoral Fellow in the laboratory of Mirko Trajkovski, University of Geneve (Switzerland)

Juan Antonio Sanchez-Alcañiz. Ph.D. Student joint with Oscar Marín from 2007-2012.

Current position: Postdoctoral Fellow in the laboratory of Richard Benton (http://www.unil.ch/cig/page44404_en.html), at CIG UNIL University of Lausanne (Switzerland)

Erik Mire. Postdoctoral Fellow from 2008-2011

Current position: Postdoctoral Fellow in the laboratory of Fanny Mann (http://www.ibdml.univ-mrs.fr/equipes/equipe_gb.php?id=105) at IBDML, Marseille (France).

Cristina Merino. Laboratory Technician

Lisa Bluy. Laboratory Technician 

Noelia García. Laboratory Technician

Elka San Martín. Laboratory Technician